The Cosmeceutical Potential of the Yellow-Green Alga Trachydiscus minutus Aqueous Extract: Preparation of a Natural-Based Dermal Formula as a Proof of Concept

In the present study, selected cosmeceutical properties of aqueous extracts from microalgae strain Trachydiscus minutus were assessed and compared with those obtained using three widely used Chlorella strains (C. vulgaris, C. sorokiniana, minutissima). Among all extracts, T. showed highest total antioxidant capacity (TAC) inhibitory potency towards elastase, suggesting potential activity in controlling skin aging. Furthermore, cytotoxicity, anti-inflammatory UVA protection extract evaluated employing normal human dermal fibroblasts (NHDF) keratinocyte HaCaT cells. The results that was able to significantly inhibit transcription marker genes involved inflammation [interleukin-6 (IL-6), interleukin-8 (IL-8) tumor necrosis factor alpha (TNFα)]. addition, treatment NHDF cells ameliorate UVA-induced cell damage by decreasing accumulation reactive oxygen species (ROS). Extracts formulated into a care cream an gel. Both formulas exhibited excellent compatibility stability. Comprehensively, these suggest displays promising providing antioxidant, anti-aging, activities, therefore has for use.